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PMC 9559827

No topical agent has demonstrated sustained cellulite reduction in rigorous clinical trials

Average weight regain: 7% of total body weight by 12 months post-discontinuation , representing approximately two-thirds of the weight they had lost

However, in March 2025, Federal Health Minister Mark Butler wrote to the PBAC to seek their expert advice on equitable access to obesity medicines through the PBS, recognising the potential benefits but also the significant cost to the healthcare system of subsidising these medicines, the spokesperson told newsGP

The mechanism: homocysteine drives endothelial oxidative stress, impairs nitric oxide signalling, promotes platelet aggregation, and accelerates arterial wall damage

Action Results Are Very Fast Acting: The gel begins to take effect as quickly as 30 minutes